Ernane Claudio de Souza
University of Iowa
From Brazil
From Brazil
Pharmacist & Pharmaceutical Scientist,
PhD Candidate at University of Iowa
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Local University of Iowa student Ernane de Souza selected for annual outreach effort highlighting scholarship and research
Ernane de Souza of Carangola, Minas Gerais, Brazil is one of 64 students at the University of Iowa featured in an annual outreach effort designed to shine a bright light on their scholarship and re...
February, 13 2018 - Verified by University of Iowa
Class of 2018
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August, 22 2017 - Verified by University of Iowa
PhD Candidate at The University of Iowa
Discovered and characterized a byproduct from an organic reaction as a new inhibitor of thrombin, an important enzyme involved in blood coagulation;
Designed, synthesized and characterized a panel of 3-(4-hydroxyphenyl)propionate oligomeric analogs to establish structural requirements for thrombin inhibition;
Evaluated a panel of N-desulfonated/N-acylated heparin derivatives for direct thrombin inhibition;
Participated in evaluation of lead modified-heparin derivatives in cell viability assays;
Synthesized N-arylacyl O-sulfonated aminoglycosides for evaluation towards thrombin inhibition;
Used enzyme kinetics assays to determine mode of inhibition;
Synthesized a panel of C-7 modified fluoroquinolones designed to combat bacterial resistance;
Wrote research manuscripts and reports, prepared and presented posters and oral presentations at scientific conferences and seminars.
August 2013 - Present
